CONNECT 2024 | Alzheimer's Disease Beyond Amyloid: immune, metabolic, environmental, and microbial contributors to the risk of development | Medeya Tsnobiladze, ND




Cost: Non-members: $65 | Member: $35 | Student: $15

For more than three decades, amyloid accumulation was considered as exclusively pathologic factor. Treatments approaches targeting amyloid were perceived as the most promising. Yet, after years of research and a handful of medications developed, diagnosed patients face essentially the same outcome perspectives as before. These underwhelming results encouraged researchers to look at other factors that might both contribute to the initiation of the processes contributing to AD pathophysiology and accelerate the clinical degression of patients. Amyloid has been reviewed and determined as a viable candidate to be a molecule of innate immunity. Various microbial presence was demonstrated to be colocalized with amyloid plaques, and antimicrobial treatments appeared to be statistically significant risk modifiers. Additionally, environmental exposures and state of internal metabolic balance (or imbalance) appear to play a significant role in stability of central nervous system and its ability to withstand against factors promoting AD development. In this presentation we will review the most significant findings accumulated over the past decade from the point of most impactful on treatment approaches and on improvement of patients' quality of life.

Dr. Medeya Tsnobiladze is a Naturopathic physician at Fairfield Family Health in Connecticut. She holds a M.S. degree in Biophysics from Moscow Institute of Physics and Technology and she trained in a PhD program in Neuroscience at Russian Academy of Medical Sciences. She received her Doctor of Naturopathic Medicine and her Master in Acupuncture from the University of Bridgeport in Connecticut. Upon graduation, she became a professor teaching naturopathic medical students and physician assistant students for 12 years before transitioning to a full-time medical practice. Dr. Tsnobiladze is a member and presenter for the International Lyme and Associated Diseases Society (ILADS) and has completed a fellowship in Integrative Neurology. Her main clinical interests include the interplay of immunology, neurology, and endocrinology.


**This presentation is worth 1 Category 1 CE, including .25 pharmacology, for Washington-licensed NDs.**

Originally presented May 3rd - 5th, 2024, at WANP's CONNECT 2024 conference.